Lidocaine vs. Bupivacaine: The Battle of the Numbing Agents for Premature Ejaculation

Lidocaine vs. Bupivacaine: Which One Will Keep You Going Without Killing the Mood?

Written by: Dr. Brian Steixner

Key Takeaways

Lidocaine is the best choice for delay sprays—fast-acting, effective, and safe.

Bupivacaine is too strong and can lead to prolonged numbness (and potential toxicity).

Follow lidocaine spray application instructions to avoid over-numbing yourself or your partner.

Natural alternatives exist , but they take time and consistency.

Popstar Delay Spray is the top choice for a high-quality lidocaine-based PE solution.

Premature ejaculation (PE) is the ultimate unwelcome surprise—like your WiFi cutting out right before a movie’s big reveal. If you’re finishing the main event before the opening credits are done, you’re not alone. PE is one of the most common sexual health concerns, but the good news is that science has some solid solutions.

One of the most effective treatments? Delay sprays. These desensitizing sprays for men can help extend your performance by reducing sensitivity—but not all numbing agents are created equal. Lidocaine and bupivacaine are two major players in the game, but which one should you trust with your most sensitive assets? Let’s break it down.

How They Work: The Science of Staying Power

Both lidocaine and bupivacaine are local anesthetics that block nerve signals, preventing you from feeling sensation as intensely. But they have some key differences.

Lidocaine: Fast-Acting and Effective

Lidocaine is like a quick pit stop—it gets the job done efficiently and lets you get back on the road. It starts working within minutes and lasts for about 30–60 minutes, giving you just the right amount of desensitization without turning things into a complete blackout down there.

Bupivacaine: The Overachiever (But Not in a Good Way)

Bupivacaine lasts much longer—sometimes several hours. While that sounds great on paper, in reality, it can mean feeling nothing for way too long. And let’s be honest, if you wanted zero sensation, you’d be watching paint dry instead.

Effectiveness for Premature Ejaculation: Does It Work or Just Make You Numb?

Why Lidocaine Wins the Popular Vote

Lidocaine is the go-to ingredient in most over-the-counter desensitizing sprays for men, including the best-in-class Popstar Delay Spray. It strikes the perfect balance—reducing sensitivity enough to help you last longer while still letting you feel something (because, you know, pleasure is kind of the point).

Bupivacaine: Too Much of a Good Thing

Bupivacaine, on the other hand, is almost too effective at numbing. It can significantly dull pleasure for both you and your partner, making it feel like you're doing your taxes instead of having sex. Plus, there’s a greater risk of toxicity if too much is absorbed into your system—hard pass.

Safety First: Side Effects and Risks

Lidocaine: Mostly Smooth Sailing

Lidocaine is generally safe when used as directed. The biggest risks? Temporary numbness that lasts a little longer than expected or mild skin irritation. If you overdo it, it might rub off on your partner—literally—so always follow the lidocaine spray application instructions to avoid awkward surprises.

Bupivacaine: A Little Too Potent

Bupivacaine is way stronger, which means a higher risk of systemic absorption. If too much gets into your bloodstream, it can lead to serious issues like cardiovascular complications (which, spoiler alert, is not sexy). That’s why it’s not commonly used in delay sprays.

Lidocaine vs. Benzocaine vs. Prilocaine: The Other Players in the Game

If you’re exploring your options, you might have heard of lidocaine-prilocaine cream for PE (a.k.a. EMLA cream for premature ejaculation) or benzocaine-based products. Here’s how they stack up:

  • Lidocaine vs. Benzocaine for PE : Benzocaine takes longer to kick in and isn’t as strong as lidocaine.

  • Lidocaine-Prilocaine Combo : Found in EMLA cream, this mix offers a gradual numbing effect that some men prefer.

  • Lidocaine vs. Bupivacaine : We’ve covered this—lidocaine is the clear winner.

Application Instructions: How to Use Lidocaine Spray Like a Pro

To get the most out of a desensitizing spray for men, follow these simple steps:

  1. Clean and dry the area before applying.

  2. Spray 1-3 times on the most sensitive areas (usually the tip and underside of the penis).

  3. Wait 5-10 minutes for it to absorb.

  4. Wipe off excess before action to avoid numbing your partner.

Overdoing it can lead to excessive numbness, so start with a small amount and adjust as needed.

Natural Alternatives to Delay Sprays

Not into sprays? You’ve got options:

While these require a bit more effort than a quick spritz of lidocaine, they can be great long-term solutions.

Final Thoughts: Keep the Fun, Ditch the Premature Finish

When it comes to premature ejaculation treatment, lidocaine sprays are the MVP. They help you last longer without turning intimacy into a numb, awkward mess. Bupivacaine? Too strong, too risky, too much.

Want the best? Popstar Delay Spray is the top-tier choice for men who want control without compromise. Ready to go the distance? You know what to do.

Frequently Asked Questions

1. Is lidocaine safe for daily use?

Yes, when used as directed. Avoid overuse to prevent irritation or excessive numbness.

2. How long does lidocaine take to work?

It kicks in within minutes and lasts about 30–60 minutes.

3. Can my partner feel the spray?

Allow it to absorb for 10 minutes before intimacy. There is no need to wipe off Popstar Delay Spray. Our formula is quick-absorbing and will not transfer to your partner.

4. Are there prescription treatments for PE?

Yes— SSRIs for premature ejaculation are sometimes prescribed, but they can come with side effects like reduced libido.

5. What’s the best over-the-counter delay spray?

Hands down, Popstar Delay Spray —fast-acting, effective, and trusted by men who want better performance without losing all sensation.

Dr. Joshua Gonzalez

Dr. Joshua Gonzalez

Dr. Joshua Gonzalez is a board-certified urologist who is fellowship-trained in Sexual Medicine and specializes in the management of male and female sexual dysfunctions. He completed his medical education at Columbia University and his urological residency at the Mount Sinai Medical Center. Throughout his career, Dr. Gonzalez has focused on advocating for sexual health and providing improved healthcare to the LGBTQ+ community.

Dr. Brian Steixner

Dr. Brian Steixner

Dr. Brian Steixner is a board-certified urologist and an expert in men’s sexual medicine. He completed his General Surgery and Urology training at The University of Pennsylvania and The Children’s Hospital of Philadelphia, one of the busiest and most comprehensive programs in the nation. During his career, Brian has treated thousands of men with sexual health issues including male factor infertility.