

Table of Contents
Key Takeaways
Sex and drugs may sound like fun, but most substances come with mood-killing side effects.
Chemsex can heighten pleasure but also increases health and safety risks.
Prescription options like Viagra vs Cialis or female sexual dysfunction treatments can help, but require medical oversight.
Sober sex benefits include better performance, stronger orgasms, and safer encounters.
There are plenty of safe alternatives to sexual performance drugs that don’t involve risky side effects.
Let’s Talk About the Not-So-Holy Trinity
You’ve heard the phrase sex, drugs, and rock ’n’ roll. We’re skipping the power chords and groupies today and diving straight into the first two. Because while sex and drugs can sound like a match made in party heaven, the reality is more… complicated.
Do you really need sexual performance drugs (whether prescription, recreational, or something you bought from a sketchy gas station bathroom vending machine) to feel like a bedroom rock star?
Short answer: nope. And in many cases, they can do the opposite of what you want.
A study back in 1991 found that a wide variety of drugs — from everyday cold meds to hard-party substances — can mess with every phase of sexual response: desire, excitement, and orgasm. For men, the top side effects were loss of libido and erectile dysfunction, followed closely by failure to ejaculate. And before you ask: yes, even over-the-counter stuff can be a buzzkill.
But what about MDMA and sex? What about cocaine and sex? What about weed, chemsex, or even Viagra vs Cialis? Let’s break it down by the most popular picks in the “sex and drugs” starter pack — and see where pleasure turns into problems.
The Global Sex and Drugs Hit List
In 2013, the Global Drug Survey polled more than 22,000 people in the US, UK, Canada, Australia, and Europe about their bedroom habits under the influence. Here’s how it shook out:
Alcohol : The reigning champ, with 58.5% of men and 60.4% of women saying they’ve had sex after drinking.
Marijuana : 37% of men and 26.3% of women said they’d gotten busy after lighting up.
MDMA : 15.5% of men and women alike — the drug that scored the highest for enhancing sexual pleasure.
Cocaine : 10.2% of men and 9.7% of women tried mixing it with sex.
Interestingly, MDMA was the only one consistently reported to enhance sex, though marijuana and cocaine also had some positive reviews.
But if you zoom into the chemsex world — sex enhanced by drugs like methamphetamine, mephedrone, and GHB/GBL — you’ll find a very different risk profile. Chemsex started in gay male communities but has spread across orientations in recent years. It can make sex last hours…but also brings a laundry list of health hazards.
The Not-So-Sexy Side Effects
Here’s the buzzkill portion of our program.
Meth and Mephedrone : Skyrocketing dopamine, extreme euphoria, and sometimes days of arousal — followed by paranoia, heart issues, hallucinations, and addiction. Also, overdose and death are not exactly great foreplay.
GHB/GBL : Known as “date rape drugs” for a reason. A tiny dose can tip someone into unconsciousness, making consent impossible.
MDMA : Euphoria and touch sensitivity, yes. But also the risk of seizures, panic attacks, overheating, and rare fatalities.
Marijuana and sexual performance : While some swear it heightens sensation, weed can also cause erectile dysfunction, dizziness, nausea, and dry mouth (not cute mid-makeout).
Alcohol : It might lower inhibitions, but it can also lower your ability to get or keep it up, delay orgasm, and — with long-term use — shrink your testes and tank your libido.
The risks of mixing drugs and sex aren’t just about physical side effects — they include STIs, unwanted pregnancies, and sexual assault, especially if one or both partners can’t consent.
Prescription Players: Viagra, Cialis, and Friends
For those dealing with erectile dysfunction, the world of PDE5 inhibitors like Viagra and Cialis can feel like a miracle. These drugs help blood flow to the penis, making erections easier to get and maintain. Viagra kicks in faster, while Cialis lasts longer — it’s like choosing between a sprint and a marathon.
If ED is linked to low testosterone, testosterone therapy for ED can help, delivered via gel, patch, injection, or implant. But testosterone isn’t just for men — women experiencing low libido can sometimes benefit, too.
For women specifically, options like Addyi and Vyleesi target sexual desire. Addyi is a daily pill, while Vyleesi is an injection you take before intimacy. And localized estrogen therapy can improve arousal and comfort by boosting blood flow and lubrication.
That said, even these “safe” female sexual dysfunction treatments and ED meds come with possible side effects and medical restrictions — especially for people with heart issues.
The Case for Sober Sex
Here’s the thing — the sober sex benefits are seriously underrated. Without drugs or alcohol in your system, you’re more likely to:
Get and stay fully aroused
Experience more intense orgasms
Remember the fun the next morning
Give (and get) clear, enthusiastic consent
Avoid the scary side of sex and drugs: sexual dysfunction, accidents, and legal trouble
If you’re looking for safe alternatives to sexual performance drugs, there are plenty. Think pelvic floor exercises, better sleep, a nutrient-rich diet, and natural supplements like the Popstar Volume + Taste Supplement for stronger, tastier climaxes without the sketchy side effects.
Consent and Substance Use
We can’t talk about sex and drugs without talking about consent and substance use. The golden rule: if someone’s impaired, they can’t consent. Period. Even if you think they’re “fine,” intoxication affects judgment, boundaries, and memory.
Sober sex isn’t just about avoiding physical risks — it’s about building trust, connection, and hot, mutual enjoyment that doesn’t rely on chemical courage.
Conclusion: Keep the Thrill, Skip the Risk
Sex should be exciting, not a gamble with your health or safety. While the cocktail of sex and drugs might seem tempting, the reality is often a mix of unpredictable highs and long-term lows.
If you want mind-blowing sex without the scary side effects, there are better, safer ways to get there — from fitness and nutrition to expert-formulated bedroom boosters like Popstar Volume + Taste Supplement and Popstar Delay Spray that actually work.
You don’t need a pill from a stranger at a club to be a rock star in bed. You just need the right tools, the right partner(s), and a body that’s firing on all cylinders.
Frequently Asked Questions
Does MDMA make sex better?
Some report enhanced sensation and emotional connection, but it comes with serious physical risks, including overheating, seizures, and panic attacks.
Is chemsex always dangerous?
Chemsex increases the risk of overdose, STIs, and addiction. While not every experience ends badly, the dangers are significant.
What’s the difference between Viagra and Cialis?
Viagra works faster but wears off sooner. Cialis takes longer to kick in but can last up to 36 hours.
Can marijuana improve sexual performance?
Some say yes, but marijuana can also cause ED and other performance issues.
What’s a safe alternative to sexual performance drugs?
Pelvic floor exercises, healthy lifestyle habits, and natural supplements like Popstar Volume + Taste are great options.
Frequently Asked Questions

Dr. Gonzalez Answers
Popstar Labs cofounder Dr. Joshua Gonzalez is a board-certified urologist and Sexual Medicine expert, here to answer your questions
WHAT IS POPSTAR?
POPSTAR is a men’s sexual health and wellness brand dedicated to improving confidence, pleasure, and effectiveness in the bedroom. Founded and developed by two doctors specializing in sexual medicine, our products help you have the healthiest, confident, and powerful orgasms imaginable.
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Popstar is the first physician-formulated daily supplement designed to support complete semen health. Developed by leading urologists specializing in sexual medicine, Popstar promotes semen volume, improves taste and enhances sperm health — all to help create awesomer orgasms!
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Results may vary, but most men start to see a difference after 2-3 weeks. Be patient and remember to take 4 Popstar pills daily with 16 ounces of water for optimal results.
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Each bottle contains 120 pills and will last 30 days per person when taken as recommended. Popstar should be taken every day for the best results. The recommended dosage is 4 pills once a day with 16 ounces of water.
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Yes, Popstar is 100% vegan.
WHAT OTHER PRODUCTS DOES POPSTAR MAKE?
POPSTAR is developing a full array of products that help address real sexual health concerns including semen health, premature ejaculation, erectile dysfunction, and sexual confidence — A place where people could find education and solutions from real doctors and with real data. We are here to support you in one goal – leading a healthy and fulfilling sex life and finding your ultimate orgasm.
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Supplement Facts
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† Daily Value (DV) not established
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Subscription benefits:
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Our revolutionary, patented men's semen volume supplement for bigger loads was created by the country’s top urologists specializing in sex medicine and the first to focus on complete semen health. Physician formulated, Popstar is a daily supplement that supports sperm health, promotes sperm volume, and enhances the taste of semen.
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Zinc, Copper, Sunflower Lecithin, L-Arginine HCI, Bromelain, Pygeum Extract, Fructooligosaccharides
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